{"id":5759,"date":"2012-10-22T07:38:23","date_gmt":"2012-10-22T07:38:23","guid":{"rendered":"http:\/\/klsmc.com\/demo\/?p=3975"},"modified":"2025-08-21T11:44:20","modified_gmt":"2025-08-21T03:44:20","slug":"the-star-cutting-edge-leadership","status":"publish","type":"news","link":"https:\/\/klsmc.com\/uk\/en\/news\/the-star-cutting-edge-leadership\/","title":{"rendered":"[The Star] Cutting-edge Leadership"},"content":{"rendered":"<p><iframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/BYTNzuq9G40?si=rQJoQSmq165JVasA\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">\ufeff<\/span><\/iframe><\/p>\n<div>\n<div>\n<h2 style=\"font-size: 30px; text-decoration: underline;\">Using stem cells to regenerate cartilage<\/h2>\n<p>by Alvin Ung<\/p>\n<\/div>\n<div>\n<p><strong>A team of Malaysian doctors achieved success and gained international attention by being innovative, passionate \u2013 and a little bit crazy.<\/strong><\/p>\n<p>ON a quiet weekend in 2011, hand surgeon Dr Ranjit Singh Gill flexed his fingers as he watched a limousine and police outriders pull up to the front entrance of the Kuala Lumpur Sports Medicine Centre (KLSMC).<\/p>\n<p>A middle-aged man emerged from the car flanked by bodyguards. Dr Ranjit Singh greeted his patient. The whole group crowded into an elevator which took them to the fifth floor where a magnetic resonance imaging (MRI) machine awaited. The bodyguards stood sentry outside.<\/p>\n<p>\u201cMy arm has been bothering me,\u201d the patient told Dr Ranjit Singh. After he gently flexed his patient\u2019s arm and studied the MRI scans, he suggested that the patient undergo keyhole surgery and five rounds of stem cell injections.<\/p>\n<p>These stem cells would repair the injured area and regenerate the cartilage tissue. The treatment was so simple, it was almost too good to be true.<\/p>\n<p>In fact, global experts in the field of orthopaedics are divided over the use of adult stem cells to repair cartilage.<\/p>\n<p>\u201cCartilage basically does not heal,\u201d Dr Hubert Kim, director of the Cartilage Repair and Regeneration Center at the University of California, San Francisco (UCSF) Medical Center, is quoted as saying in an interview on the centre\u2019s website.<\/p>\n<figure id=\"attachment_4177\" aria-describedby=\"caption-attachment-4177\" style=\"width: 800px\" class=\"wp-caption alignnone\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-4177\" src=\"https:\/\/klsmc.com\/uk\/wp-content\/uploads\/2025\/08\/Cover_lr.png\" alt=\"Cover_lr\" width=\"800\" height=\"411\" \/><figcaption id=\"caption-attachment-4177\" class=\"wp-caption-text\">\u201cDoctors should always take the route that\u2019s safest for the patient. But sometimes, the textbook solution is not necessarily the safest way of doing things. You need to continuously challenge yourself with difficult decisions. It\u2019s a big responsibility.\u201d &#8211; Dr. Ranjit.<\/figcaption><\/figure>\n<p>Dr Ranjit Singh\u2019s treatment, developed in Malaysia, flew in the face of medical textbooks. It took guts to suggest the road less travelled.<\/p>\n<p>\u201cDoctors should always take the route that\u2019s safest for the patient. But sometimes, the textbook solution is not necessarily the safest way of doing things,\u201d Dr Ranjit Singh told me in a series of interviews, as he recounted treating this unique patient, who shall go unnamed because of doctor-patient confidentiality.<\/p>\n<p>\u201cYou need to continuously challenge yourself with difficult decisions. It\u2019s a big responsibility.\u201d<\/p>\n<p>That is leadership on the cutting-edge, metaphorically and medically speaking. Thanks to its doctors\u2019 research on stem cell therapy, the KLSMC has emerged as a clinical and research powerhouse for orthopaedic work globally, achieving a pace of innovation unmatched by most private practices in the country.<\/p>\n<p>The doctors here have temerity, talent and a good track record to provide cutting-edge \u2013 sometimes experimental \u2013 treatments to rival the best in advanced nations.<\/p>\n<p>The KLSMC journey toward the cutting-edge began in 2005 when Dr Ranjit Singh\u2019s colleague, orthopaedic surgeon and KLSMC founder Dr Saw Khay Yong, successfully regenerated cartilage in the knee joints of goats.<\/p>\n<p>Then, Dr Saw tried to regenerate normal cartilage in patients\u2019 knees by injecting the patients\u2019 own blood stem cells into their knees after drilling holes into the underlying bone. That worked too.<\/p>\n<p>Drawing on Dr Saw\u2019s success with knees, Dr Ranjit Singh tested out the articular cartilage regeneration procedure on the limbs of three patients. Again, success. Cartilage could be regrown.<\/p>\n<p>The early studies, published in international scientific journals, drew interest from orthopaedic specialists and university lecturers from the United States and Britain, who flew to Kuala Lumpur to learn the latest techniques from KLSMC.<\/p>\n<p>\u201cTheir technology will change orthopaedic surgery forever,\u201d Dr Adam Anz, a Florida orthopaedic surgeon, said in an interview.<\/p>\n<p>Exciting as that was, Dr Ranjit Singh was now recommending this relatively new procedure \u2013 tested on a bunch of goats and a few people \u2013 to one of the most famous people in Malaysia.<\/p>\n<p>\u201cThis procedure isn\u2019t in the medical textbooks,\u201d Dr Ranjit Singh told his patient. \u201cWill you consider it?\u201d<\/p>\n<p>\u201cI\u2019ll think about it,\u201d the patient said.<\/p>\n<p>Dr Ranjit Singh shook his head as he watched his patient hop into the limo and leave the hospital accompanied by the wail of police sirens.<\/p>\n<p>Was he brilliant? Or crazy? Probably both, he concluded.<\/p>\n<p>It is the norm for doctors to leave the public health system to join private practice. It is unusual for a half-dozen orthopaedic specialists, headed by Dr Saw, to leave their private practice to start their own hospital in Bukit Damansara.<\/p>\n<p>It\u2019s extremely rare for such doctors to embark on stem cell research \u2013 even while they were designing the hospital building and paying off mortgages and praying for patients to show up. And it\u2019s probably crazy to think of even setting up a stem cell lab in a country where research infrastructure is relatively sparse.<\/p>\n<p>\u201cIs there a better way of doing things in hospitals?\u201d Dr Saw mused aloud during an interview at Nerofico, an Italian restaurant on the ground floor of KLSMC, which serves gourmet food to its patients. \u201cWe dreamed of seeing and scanning the patient the same day, and then doing surgery the next day.\u201d<\/p>\n<p>\u201cWe were passionate and obsessive about wanting to do things properly. But logically, the risk was still too high to set up a centre so big,\u201d Dr Ranjit Singh added, as he gestured broadly toward the nine floors of the hospital, which includes a pharmacy, a laboratory, operating theatres, a gorgeous high-ceilinged physiotherapy centre on the eighth floor and a rooftop hydrotherapy pool.<\/p>\n<p>\u201cSo we needed the final magic ingredient: you have to be a little bit crazy.\u201d<\/p>\n<p>Their craziness has paid off. Thanks to their original research conducted with Universiti Putra Malaysia in 2005, Dr Saw and his colleagues began providing stem cell therapy for sports-related and other common joint injuries.<\/p>\n<p>Soon they found themselves treating national athletes, weightlifters and international patients.<\/p>\n<p>In May this year, world No 1 badminton player Datuk Lee Chong Wei injured his right ankle. Most Malaysians wrote off his chances of competing at the London Olympics. Lee went to KLSMC for stem cell injections into a torn ligament. He recovered quickly.<\/p>\n<p>A few months later, Dr Saw found himself joining millions of Malaysians cheering on Lee in the breathtaking Olympic final against Lin Dan. \u201cI was watching his ankle all the time and hoping he wouldn\u2019t twist it again.\u201d<\/p>\n<p>Dr Saw\u2019s pioneering work in regenerating knee cartilage has won praise from the editors of the peer-reviewed Journal Of Arthroscopic And Related Surgery. In two separate editorials, editor-in-chief Professor Gary Poehling urged readers to study the research published by Dr Saw in Malaysia and his co-authors in North Carolina and Alaska.<\/p>\n<p>Prof Poehling described the diagrams as \u201camazing\u201d and \u201cpriceless\u201d and concluded that \u201cstem cells have vast potential\u201d. Dr Saw continues to publish papers that show evidence that articular cartilage in the knee joint can be regenerated.<\/p>\n<p>The KLSMC doctors\u2019 research has now broadened stem cell treatment into cartilage, soft tissue, nerves and tendons \u2013 building on ground-breaking work carried out by specialists in multiple fields throughout the world.<\/p>\n<p>\u201cRight now this is the best possible treatment ever,\u201d said Dr Anz, who has flown to Malaysia several times to learn new techniques and collaborate with Dr Saw.<\/p>\n<p>\u201cWe want to give our patients the best treatment possible. Once they see it involves stem cells \u2013 and they see how it\u2019s so easy to harvest, easy to process, easy to store and easy to inject into (a) patient \u2013 that\u2019s going to change the world.\u201d<\/p>\n<p>Currently, Dr Saw and his colleagues are planning a worldwide multicentre trial. The goal is to prove to the global medical fraternity that this form of stem cell treatment works.<\/p>\n<figure id=\"attachment_4178\" aria-describedby=\"caption-attachment-4178\" style=\"width: 800px\" class=\"wp-caption alignnone\"><img decoding=\"async\" class=\"size-full wp-image-4178\" src=\"https:\/\/klsmc.com\/uk\/wp-content\/uploads\/2025\/08\/Cover2_lr.png\" alt=\"\" width=\"800\" height=\"404\" \/><figcaption id=\"caption-attachment-4178\" class=\"wp-caption-text\">&#8220;As we will be the principal investigator, a worldwide randomised control trial will showcase biotechnology in Malaysia. You\u2019ll change the way cartilage injuries are treated. And you\u2019ll rewrite the textbooks.&#8221; &#8211; Dr. Say Khay Yong<\/figcaption><\/figure>\n<p>\u201cAs we will be the principal investigator, a worldwide randomised control trial will showcase biotechnology in Malaysia,\u201d Dr Saw said. \u201cYou\u2019ll change the way cartilage injuries are treated. And you\u2019ll rewrite the textbooks.\u201d<\/p>\n<p>Dr Ranjit Singh wasn\u2019t out to rewrite textbooks when he began treating his patient with the arm problem. All he wanted to do was provide the best care possible. So he sent an e-mail to two famous orthopaedic surgeons asking a second opinion on whether or not he should inject stem cells into his famous patient.<\/p>\n<p>\u201cAre you crazy?\u201d a doctor from France replied. However, Dr Ranjit Singh\u2019s mentor urged him to go for it. Faced with two opposite opinions, he knew what he had to do: he went for it.<\/p>\n<p>\u201cIt will take several weeks for the stem cells to recognise the injured area and regenerate the tissue, which will reattach back to the bone,\u201d he explained to his patient.<\/p>\n<p>After the keyhole surgery, the patient returned to KLSMC five times for stem cell injections.<\/p>\n<p>Four months later, Dr Ranjit Singh met his patient and asked: \u201cHow\u2019s the arm?\u201d<\/p>\n<p>\u201cPerfectly fine,\u201d the patient replied.<\/p>\n<p>As the surgeon reflected on his unique patient \u2013 just one among many cases he has treated \u2013 perhaps the biggest leadership lesson he learned is to do what you love.<\/p>\n<p>\u201cDoing what you love will drive you all the way \u2013 to be focused and persistent, to practise and practise, and finally to have that extra bit of craziness that pushes you forward.<\/p>\n<p>\u201cIf you love your job, you\u2019ll do well in it. And if you do well in it, you\u2019ll love your job,\u201d he said.<\/p>\n<hr \/>\n<\/div>\n<div><\/div>\n<div>\n<h2 style=\"font-size: 30px; text-decoration: underline;\">Dr Ranjit Singh Gill\u2019s toughest case<\/h2>\n<p>A MICROSURGEON typically performs surgery on blood vessels and nerves using extra-small surgical tools, micro-sutures and a microscope to magnify the area.<\/p>\n<p>The work of reattaching even one blood vessel is delicate, time-consuming and exhausting. You need constant visual contact with the microscope during surgery, and you need to maintain correct posture to minimise the amount of hand tremor.<\/p>\n<p>Hand surgeon Dr Ranjit Singh Gill\u2019s most challenging case occurred when a man got his hand caught in a circular saw machine.<\/p>\n<p>The machine amputated the patient\u2019s hand through the wrist. The hand then flipped back into the machine, which severed all the fingers.<\/p>\n<p>\u201cWe had to reattach the stump of the hand to the wrist, and then individually reattach all the fingers,\u201d Dr Ranjit Singh said.<\/p>\n<p>The man\u2019s hand, though not fully restored, was saved \u2013 and functional.<\/p>\n<p>Leadership lesson: Get things right the first time. In a hand injury, as with any human encounter, the final outcome depends on the first treatment.<\/p>\n<p>\u201cHands don\u2019t bore me. Hands are attached to the person. When you examine the hand, you\u2019re examining how his emotions, appearance and livelihood are being affected,\u201d Dr Ranjit Singh said.<\/p>\n<hr \/>\n<h2 style=\"font-size: 30px; text-decoration: underline;\">Moving from frustration to fruitfulness<\/h2>\n<p>EVERYONE has experienced prolonged and extreme frustration. Leaders don\u2019t wallow in learned helplessness. Here\u2019s how to move from extreme frustration to extraordinary fruitfulness.<\/p>\n<p><strong>Name the plan<\/strong><\/p>\n<p>List everything about the problem that frustrates or perplexes you. You can\u2019t move on to extraordinary fruitfulness before naming the reality.<\/p>\n<p>Dr Saw Khay Yong, an orthopaedic specialist, was unhappy with how far his clinic was from the operating theatre and physiotherapy units. The wait times \u2013 for MRI scans, surgery and therapy \u2013 were also far apart.<\/p>\n<div id=\"content_0_inlineAd\"><\/div>\n<p>\u201cWe were frustrated. There had to be a better way of doing things,\u201d he said.<\/p>\n<p><strong>Fan the passion<\/strong><\/p>\n<p>Ask yourself what you\u2019d love to see. If you had a magic wand, what would you want to see happen? Dr Saw wanted to deliver the ideal patient care.<\/p>\n<p>\u201cWe wanted a place where the patient, the doctor, the physiotherapist and the nurse worked together in the same room.\u201d<\/p>\n<p><strong>Form a winning coalition<\/strong><\/p>\n<p>He also wanted to push the boundaries of evidence-based medicine in Malaysia. It was obvious he couldn\u2019t do it alone.<\/p>\n<p>He invited other orthopaedic surgeons \u2013 experts in the hand, shoulders, ankles, hips and back \u2013 to join him. He collaborated with local and international universities. He shared data and techniques with top doctors who visited the centre.<\/p>\n<p><strong>Integrate medical and management expertise <\/strong><\/p>\n<p>\u201cAs a group, you draw strengths from your fellow doctors, nurses and therapists, especially to overcome your weaknesses. We kept our eyes on each other,\u201d Dr Saw said.<\/p>\n<p>That led him to an \u201caha!\u201d moment. Why not create the same team dynamics at the administrative level as well?<\/p>\n<p>\u201cWe practise as a team in our medical work, and we now practise as a team in how we run the administrative aspects of the hospital.\u201d<\/p>\n<p>Sources:<\/p>\n<ul>\n<li><a href=\"http:\/\/www.thestar.com.my\/Lifestyle\/Health\/2012\/10\/22\/Using-stem-cells-to-regenerate-cartilage\/\" target=\"_blank\" rel=\"noopener\">Using Stem Cells to Regenerate Cartilage<\/a><\/li>\n<li><a href=\"http:\/\/www.thestar.com.my\/Lifestyle\/Health\/2012\/10\/22\/Dr-Ranjit-Singh-Gills-toughest-case\/\" target=\"_blank\" rel=\"noopener\">Dr. Ranjit Singh Gill&#8217;s Toughest Case<\/a><\/li>\n<li><a href=\"http:\/\/www.thestar.com.my\/Lifestyle\/Health\/2012\/10\/22\/Moving-from-frustration-to-fruitfulness\/\" target=\"_blank\" rel=\"noopener\">Moving from Frustration to Fruitfulness<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><a 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